Nicole Nasholm

Lab Manager

Pediatric Oncology

+1 541 953-6505

Publications:

IMMU-06. INVESTIGATING IMMUNOSUPPRESSIVE MECHANISMS IN THE TUMOR MICROENVIRONMENT OF HIGH-RISK NEUROBLASTOMA; AN IMMUNOCOMPETENT, MYCN-DRIVEN, NON-GERMLINE GEM MODEL.

Neuro-Oncology

Marie Menard, Lauren McHenry, Nicole Nasholm, Shannon Wong-Michalak, Edbert Lu, Erin Simonds, W Clay Gustafson, William A Weiss

Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling.

Cancer cell

Iniguez AB, Alexe G, Wang EJ, Roti G, Patel S, Chen L, Kitara S, Conway A, Robichaud AL, Stolte B, Bandopadhayay P, Goodale A, Pantel S, Lee Y, Cheff DM, Hall MD, Guha R, Davis MI, Menard M, Nasholm N, Weiss WA, Qi J, Beroukhim R, Piccioni F, Johannessen C, Stegmaier K

CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2.

The Journal of clinical investigation

Chen L, Alexe G, Dharia NV, Ross L, Iniguez AB, Conway AS, Wang EJ, Veschi V, Lam N, Qi J, Gustafson WC, Nasholm N, Vazquez F, Weir BA, Cowley GS, Ali LD, Pantel S, Jiang G, Harrington WF, Lee Y, Goodale A, Lubonja R, Krill-Burger JM, Meyers RM, Tsherniak A, Root DE, Bradner JE, Golub TR, Roberts CW, Hahn WC, Weiss WA, Thiele CJ, Stegmaier K

Phase 1 study of sirolimus in combination with oral cyclophosphamide and topotecan in children and young adults with relapsed and refractory solid tumors.

Oncotarget

Vo KT, Karski EE, Nasholm NM, Allen S, Hollinger F, Gustafson WC, Long-Boyle JR, Shiboski S, Matthay KK, DuBois SG

Absence of STAT1 in donor-derived plasmacytoid dendritic cells results in increased STAT3 and attenuates murine GVHD.

Blood

Capitini CM, Nasholm NM, Chien CD, Larabee SM, Qin H, Song YK, Klover PJ, Hennighausen L, Khan J, Fry TJ

Minor antigen distribution predicts site-specific graft-versus-tumor activity of adoptively transferred, minor antigen-specific CD8 T Cells.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Shand JC, Qin H, Nasholm N, Capitini CM, Fry TJ

Graft-versus-host disease impairs vaccine responses through decreased CD4+ and CD8+ T cell proliferation and increased perforin-mediated CD8+ T cell apoptosis.

Journal of immunology (Baltimore, Md. : 1950)

Capitini CM, Nasholm NM, Duncan BB, Guimond M, Fry TJ

Tissue Distribution of a Minor Antigen, but Not PD-1 Expression, Predicts the Antileukemia Efficacy of Adoptively Transferred, Antigen-Specific T-Cells in a Preclinical Model of Allogeneic Transplant.

Blood

Jessica C. Shand, Christian M. Capitini, Haiying Qin, Nicole Nasholm, Terry J. Fry

Alloreactivity Directed Against the Widely Distributed HY Antigen Impairs Antitumor Immunity and Results in T-Cell Dysfunction.

Blood

Jessica C Shand, Christian M. Capitini, Haiying Qin, Nicole Nasholm, Brynn B Duncan, Terry J Fry

Extracorporeal photopheresis attenuates murine graft-versus-host disease via bone marrow-derived interleukin-10 and preserves responses to dendritic cell vaccination.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Capitini CM, Davis JP, Larabee SM, Herby S, Nasholm NM, Fry TJ

W. CLAY GUSTAFSON LAB AT UCSF

Nicole Nasholm

IMMU-06. INVESTIGATING IMMUNOSUPPRESSIVE MECHANISMS IN THE TUMOR MICROENVIRONMENT OF HIGH-RISK NEUROBLASTOMA; AN IMMUNOCOMPETENT, MYCN-DRIVEN, NON-GERMLINE GEM MODEL.

Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling.

CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2.

Phase 1 study of sirolimus in combination with oral cyclophosphamide and topotecan in children and young adults with relapsed and refractory solid tumors.

Absence of STAT1 in donor-derived plasmacytoid dendritic cells results in increased STAT3 and attenuates murine GVHD.

Minor antigen distribution predicts site-specific graft-versus-tumor activity of adoptively transferred, minor antigen-specific CD8 T Cells.

Graft-versus-host disease impairs vaccine responses through decreased CD4+ and CD8+ T cell proliferation and increased perforin-mediated CD8+ T cell apoptosis.

Tissue Distribution of a Minor Antigen, but Not PD-1 Expression, Predicts the Antileukemia Efficacy of Adoptively Transferred, Antigen-Specific T-Cells in a Preclinical Model of Allogeneic Transplant.

Alloreactivity Directed Against the Widely Distributed HY Antigen Impairs Antitumor Immunity and Results in T-Cell Dysfunction.

Extracorporeal photopheresis attenuates murine graft-versus-host disease via bone marrow-derived interleukin-10 and preserves responses to dendritic cell vaccination.

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Nicole Nasholm